Platelet-Rich Plasma Injection

What is Platelet-Rich Plasma Used For?

  • Platelet-Rich Plasma (PRP) is indicated for the treatment of conditions such as lateral epicondylitis (tennis elbow), patellar (knee) tendonitis, rotator cuff injuries, achilles tendonitis and osteoarthritis.
  • PRP is produced by taking a sample of the patient’s own blood and separating the plasma component that is rich in platelets and void of red blood cells by spinning it at a high speed in a centrifuge.
  • Platelets secrete growth factors and cytokines (cell-signalling proteins), some of which have anti-inflammatory roles and promote healing and regeneration. 
  • The platelet-rich portion is then re-injected into the affected area.
  • A series of one to four injections may be required.
  • The procedure is performed using ultrasound or X-ray in the day surgery setting.


Prior to the Procedure

  • All blood thinning products must be stopped prior to your procedure - this includes aspirin. A nurse from Hunter Pain Clinic will advise youof the appropriate time to do so.
  • All anti-inflammatory medications must be stopped one week prior to your procedure and for one week following your procedure.
  • You are able to take your other regular medications with a sip of water on the morning of your procedure.
  • If you are an insulin dependent diabetic you will always be at the beginning of the list. Please bring your insulin with you and it will be given to you following your procedure.
  • Hamilton Day Surgery Centre staff will advise you prior to your procedure of your fasting and admission time.
    • Fasting means you must not have anything to eat, drink, smoke or chew priot to your procedure.
  • You will need to organise someone to drive you home after the procedure as you will not be able to drive for 24 hours after your procedure.


What Will Happen?

  1. You will be admitted to the day surgery by a nurse and you will be asked to change into a gown.
  2. The Anaesthetist will speak with you and place a cannula (plastic needle) into a vein in your hand.
  3. In the procedure room, you will be assisted to position on the procedure table.
  4. The Anaesthetist will give you some sedation into your vein. 
  5. Your Doctor will take a sample of your blood which will be spun in a centrifuge to extract the platelets.
  6. Once the PRP is ready, it will be injected into the affected area.
    • The procedure will take approximately 10 minutes to complete.
  7. After the procedure, you will be placed on a trolley and taken to recovery, where you will remain for approximately one hour.
  8. After having something to eat and drink, you will be discharged with a carer.


Post Procedure

  • Gentle activity and rest is recommended in the first 24 hours following the procedure. You may then return to normal activity.
  • You may experience some discomfort following the procedure. You may apply ice and elevate the affected limb.
  • A nurse from HPC will telephone you 24 to 48 hours following your procedure to check on your progress and organise a follow up appointment.


If you require further explanation of the procedure, please contact Hunter Pain Clinic nursing staff on (02) 4985 1800.

*  Image courtesy of drpnncpptak at